People refer to the ‘LMB culture’ as the thing, one of the things, that makes it special. It’s an attention to people who are willing to tackle very big problems. I mean problems that are so big that you couldn’t just solve it in a grant. The kind of problem that you could devote your life to. I was very fortunate in having mentors of Fred Sanger and César Milstein who exercised a kind of very benign mentorship but encouraged us to think big.
Recorded Adam Smith, Telephone interview recorded shortly after the prize announcement, Nobel Prize Outreach, 1 October 2018 source ↗