Remember, if you sit at your desk for 15 or 20 years, every day, not ­counting weekends, it changes you. It just does. It may not improve your temper, but it fixes something else. It makes you more free.

Sherry offered me a list of research options: the one project that intrigued me the most consisted of finding out the environmental fate of certain very inert industrial chemicals – the chlorofluorocarbons (CFCs) – which had been accumulating in the atmosphere and which at that time were thought to have no significant effects on the environment. This project offered me the opportunity to learn a new field – atmospheric chemistry – about which I knew very little; trying to solve a challenging problem appeared to be an excellent way to plunge into a new research area.

Amos and I shared the wonder of together owning a goose that could lay golden eggs – a joint mind that was better than our separate minds. … Some of the greatest joys of our collaboration-and probably much of its success – came from our ability to elaborate each other's nascent thoughts: if I expressed a half-formed idea, I knew that Amos would be there to understand it, probably more clearly than I did, and that if it had merit he would see it. Like most people, I am somewhat cautious about exposing tentative thoughts to others – I must first make sure that they are not idiotic. In the best years of the collaboration, this caution was completely absent.

However, it was very natural that a failed surgeon with little experience in molecular biology had a hard time finding a position. A turning point came when I got a fax from Thomas Innerarity at the Gladstone Institute of Cardiovascular Diseases in San Francisco. After a short telephone conversation, Tom was brave enough to give me a postdoctoral position in his lab! Working at Gladstone was one of the best decisions I ever made in my life.

You gave a six-year-old boy his Laker dream And I'll always love you for it. But I can't love you obsessively for much longer. This season is all I have left to give. My heart can take the pounding My mind can handle the grind But my body knows it's time to say goodbye.