What is the biggest obstacle you have faced professionally?

Originally asked

The American Academy of Achievement, to its honourees, its oral-history interviews

The Academy of Achievement repeatedly asks honorees to identify a major professional obstacle or challenge and describe confronting it.

You answer as yourself. Nobody on FLAPSS answers as anybody else.

Recorded Katalin Karikó said elsewhere, not written here
Adam, if you know about 10 years ago, I was here in October because I was kicked out, from Penn, was forced to retire. Then my husband supported me and said that, you know, when finally visited in Germany and found that maybe BioNTech is the right place, then he said "Just try it and I will make sure that you don't regret." Looking back in my life he supported that I would go, and for nine years I commuted to BioNTech in Germany. I did all these experiments actually, with my own hands, I was 58 years old, I was still culturing plasmids and feeding cells, so it is very unlikely.

Adam Smith, Telephone interview recorded shortly after the prize announcement, October 2023, Nobel Prize Outreach, 1 October 2023 source ↗

Others on this question

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Tony Judt Historian and essayist
This cockroach-like existence is cumulatively intolerable even though on any given night it is perfectly manageable. “Cockroach” is of course an allusion to Kafka’s Metamorphosis, in which the protagonist wakes up one morning to discover that he has been transformed into an insect. The point of the story is as much the responses and incomprehension of his family as it is the account of his own sensations, and it is hard to resist the thought that even the best-meaning and most generously thoughtful friend or relative cannot hope to understand the sense of isolation and imprisonment that this disease imposes upon its victims.
Recorded The New York Review of Books, 14 January 2010 issue, 14 January 2010 source ↗
Philip Johnson Architect; first winner of the Pritzker Prize
Then you have the clients. The care and feeding of clients is really one of the main obstacles, because you always have a client with some preconceived idea of what a house looks like, and all you want him to do is leave a check and go to Europe for a couple of years. Or leave two checks. But alas, life isn’t simple. If it were, more people would be better architects.
Recorded Academy of Achievement, Academy of Achievement interview, New Canaan, Connecticut, 1 April 2000 source ↗
Richard Feynman Theoretical physicist; Nobel laureate in Physics, 1965
At Cornell, I’d work on preparing my courses, and I’d go over to the library a lot and read through the Arabian Nights and ogle the girls that would go by.  But when it came time to do some research, I couldn’t get to work.  I was a little tired; I was not interested; I couldn’t do research!  This went on for what I felt was a few years, but when I go back and calculate the timing, it couldn’t have been that long.  Perhaps nowadays I wouldn’t think it was such a long time, but then, it seemed to go on for a very long time.  I simply couldn’t get started on any problem: I remember writing one or two sentences about some problem in gamma rays and then I couldn’t go any further.  I was convinced that from the war and everything (the death of my wife) I had simply burned myself out.
Recorded Excerpt from “Surely You’re Joking, Mr. Feynman”, Engineering and Science / Caltech Magazine, 1985 source ↗
Tom Lubbock Art critic
For me, no word comes without prior thought. No sentence is generated without effort. No formulation is made automatically. I am faced continually with a mystery that other people have no conception of, the mystery of the generation of speech. There is no command situation, it goes back and back and back. Where the self lies at the heart of the utterance, the speaker generating the word, is always clouded. This is true for everyone, but for most people this is not something to think about. The generation of words is automatic. For me, that automatic link is broken. Word generation involves strain, guesswork, difficulty, imprecision.
Recorded The Observer, from the journals he kept between 2008 and 2010, 7 November 2010 source ↗

More from Katalin Karikó

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Question What is the book you have given most as a gift, and why? Taste & recommendation
When I was 16 years old, I read the book from Hans Selye. Hans Selye is a Canadian scientist, but he was Hungarian so his book was translated to Hungarian. His mantra was that you have to focus on things that you can change. Many young ones are giving up because they can see that their friends or their colleagues are advancing, and it seems that they do less and somehow, they get higher salary and promoted. I told that if you notice that then you already took away your attention what you can change. Because you cannot change that.
Recorded Adam Smith, Telephone interview recorded shortly after the prize announcement, Nobel Prize Outreach, 2 October 2023 source ↗

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