When I was this young assistant at the University of Groningen my responsibility was for four beds, or rather the patients in four beds. That was all I had to do. And, one of these patients was a young man, 22 years old, who slowly and miserably died from renal failure. He became blind, he vomited, and it was a miserable death. And I, as a very, very young physician, had to tell his mother, in a black dress and a little white cap like the farmers have, that her only son was going to die. I couldn’t do a damn thing about it. So, I began to think, “If I could just every day remove as much urea as this boy creates, which is about 20 grams, then the boy could live.” Well, he died, but I began to work on that.

Good question. The novel began with Sten and his story, which then suggested the rest. I always follow that first line and always write organically, in sequence. This allows me to make the discoveries I need to as I progress. I don’t really concern myself with questions of which character takes precedence—again, that lies outside my purview. I see this as a kind of ensemble piece, I suppose, like the novel that precedes it, San Miguel , told from the perspective of three women.

My videos are architecture for sets of ideas. The structure of the video houses those ideas.

I don’t begin with a material. I begin with a problem. If a material can solve that problem, then I become interested in it. Sometimes it is paper, sometimes timber, sometimes carbon fibre. There are many materials we still don’t use efficiently. I think there is always room to discover new possibilities, every project presents a different problem, and I am always thinking about how to solve it more simply, with fewer materials or a better structure. I think every material has good and bad qualities. The important thing is understanding them and using them appropriately.