I have the same academic disease that any academic will understand, that I get focused on the interesting because that’s appealing to me. Most of the time, most answers are boring. “It’s a respiratory disease. Wear a mask.” That’s a boring example. Trying to be too clever, too smart, almost too contrarian sometimes — I would say that is something that I fight in myself because, like a lot of academics and a lot of intellectual people, I like the answers that surprise me.

I’m too quick to jump to a negative conclusion. For example, if I’ve had a book come out recently and I’m with a friend who doesn’t mention it, instead of thinking, “This person hasn’t mentioned my book because they’re busy and haven’t had time to purchase it, much less read it, and that doesn’t mean that they don’t like me,” I will go to, “This person doesn’t care about me,” which is such a terrible, self-centered way to think. People really are busy and their world doesn’t stop just because I’ve published a novel.

I probably want to be liked too much. This is one difference between me and Steve Levitt . Steve Levitt is also much smarter than me and much more successful than me. And that doesn’t bother me at all, but he said he also doesn’t care what anyone thinks about him, or doesn’t seem to care what anyone thinks about him. I actually do care what people think about me. I’d quite like people to think I’m a nice guy, so I’m probably self-censoring at times. Say, maybe I won’t say that because people wouldn’t like that. And that’s probably a fault in a newspaper columnist — you probably shouldn’t care what people think about you, but that’s the way it is.

I question everything. This is also my greatest intellectual habit.

No, because I started working on ribosomes when I was a post doc, in 1978, when it would have been impossible, really, to solve it. But, it was just a fundamental problem in biology. And we felt, no matter, anything we do to chip away at the problem would be useful. So it was more that that attracted me. And I think the fact that it was large and kind of difficult to come to grips with, yes, it was attractive. Really what was attractive was that it was a fundamental problem.

Well, I'll be honest with you. I was a theoretical physicist but my Ph.D. work was on a problem that was not particularly interesting to me at the time. And I used to subscribe to Scientific American and I found that there were all these wonderful discoveries happening in biology and I also knew that a number of physicists had gone into biology and been successful. So, I decided to switch.