At first the research did not seem to be particularly interesting – I carried out a systematic search for processes that might destroy the CFCs in the lower atmosphere, but nothing appeared to affect them. We knew, however, that they would eventually drift to sufficiently high altitudes to be destroyed by solar radiation. The question was not only what destroys them, but more importantly, what the consequences are.

One setback after another, we shook it off and skated to the next opportunity. Each time, we gain skills and strengthen our character. No setback that comes our way doesn't look like an opportunity these days.

They’re not failures, you try something and it doesn’t work, and some people, you know, get fed up with this, and I’ve known some of my friends and colleagues who have just decided to give up science because they can’t stand it, but I’ve always decided, you know, if it doesn’t work, forget it and start planning the next experiment, and that’s always exciting.

People not believing me. It's getting a little easier, but it's funny how people will say, "I don't think you can do that." Then you do it, and they say "That was great" and you say, "Well, I've got this other idea." "Naw, I don't think you can do that." So you do it again. When I said I was going to find the Titanic , no one believed it. When I said I was going to find the Bismarck , everyone believed it, and then I failed in my first attempt to find the Bismarck . So people expect you to succeed, but they don't want to stick their own necks out, and so risk-taking can be very lonely at times. You know that classic saying, which is very true: "Failure is an orphan, but success has many fathers." I'll tell you, when I'm most at risk, I look around, and there are not a whole lot of people there. But as soon as I succeed, they say, "We were always there." And I say, "Yeah, but 500 miles behind me."

It’s very hard to give people advice, because you don’t know their personality. Personality is a big part of that. Everybody is faced with passing opportunities. Many people watch the opportunity come and watch it go. I say, if an opportunity comes and you have got the self-confidence, grab it. Ride it for a bit. If it’s not the right opportunity, do something else, but be positive about opportunities.