It was a very important finding for us because we were involved in nucleic acids. There weren’t many people interested in nucleic acids. There weren’t many people who believed that was the way to find drugs. But when we found out the structure, and we began to understand what kind of bases could be incorporated, and which ones couldn’t, and where they could be incorporated, it put a whole new dimension on it. So it had a very significant effect.

One was Roscoe Gilkey Dickinson. He had got his doctorate in physical chemistry — x-ray crystallography — in 1920. He was the first person to get a Ph.D. from California Institute of Technology. And he was continuing with x-ray crystallography, determining the structure of inorganic crystals. After I had accepted appointment as a graduate student at California Institute of Technology, A.A. Noyes, the head of the division of chemistry and chemical engineering, wrote to say that he had decided I should work with Roscoe Dickinson on determining the structure of crystals. This was really extremely fortunate for me, in my opinion. I don’t think that there was any field that was more suited to my interests, and I don’t really know why Dr. Noyes selected me out of eight or ten new graduate students to do x-ray crystallography. Dickinson had a remarkable mind. He was a very careful investigator and thinker, a very logical thinker. When he was teaching me x-ray crystallography, he also taught me to ask at each stage in the argument, “What assumptions are being made? How reliable is the conclusion that you draw? What chance is there that one of the assumptions you have made is not correct?” “You should recognize,” he said to me, “that there is in almost every investigation a lack of complete rigor. You should understand just how reliable the arguments are that you are presenting.

Very much, because he’s interested in that same kind of process. Bonnard, Matisse, Indian miniature paintings, which he collected. That’s where the light comes from, a spectral relationship within the painting itself.

Actually, I started falling in love with the films of Brian De Palma. He was the first filmmaker I ever loved, he always made genre films. They touched me more, they felt warm, and human, and unsettling. There was always his vision behind them.

Totally. I’d say parents, brothers, sisters, and don’t go far beyond that for the moment. If you’ve had a long-term relationship with an agent, that’s a whole different thing, because that agent is there to care.