Do the secret thing you know you were born to do.

That there is time. I doggedly prioritise and pursue tasks, and the day seems to open out and everything does get done. Chill.

But cancer has also ushered in new ways of being alive. Even when I am this distant from Canadian family and friends, everything feels as if it is painted in bright colors. In my vulnerability, I am seeing my world without the Instagrammed filter of breezy certainties and perfectible moments. I can’t help noticing the brittleness of the walls that keep most people fed, sheltered and whole. I find myself returning to the same thoughts again and again: Life is so beautiful. Life is so hard.

That further lessons await.

I got very interested in so-called “knockout mouse” technology. Knockout mouse is a way to study the function of genes. You know, both human and mouse have approximately 20,000 genes. With knockout mouse technology, we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology. That’s why I decided to move to the States, San Francisco

Well actually I was at home. I was doing some housework. So I was very surprised.

However, it was very natural that a failed surgeon with little experience in molecular biology had a hard time finding a position. A turning point came when I got a fax from Thomas Innerarity at the Gladstone Institute of Cardiovascular Diseases in San Francisco. After a short telephone conversation, Tom was brave enough to give me a postdoctoral position in his lab! Working at Gladstone was one of the best decisions I ever made in my life.

I strongly feel that this is, that I am able to receive this award because of John Gurdon and also many other researchers in the field. This field has a long history, starting with John Gurdon. So I feel very lucky. I may have played some important role in this long history, but it was not myself who initiated this field. So that’s my feeling right now.

I was born in Osaka, Japan. It was 45 years ago. My father has a small factory in Osaka, and we lived next to his factory

Well, I will bring this technology to clinics. I really want to help as many patients as possible. As you may know, I started my career as a surgeon 25 years ago. But it turned out that I am not talented as a surgeon