My science family came from all over the world, and members were of varied backgrounds, cultures, and abilities. The diversity in this "small world" I worked in daily provided the most stimulating environment, with many challenges and much optimism. Over the years, my research group has had close to 150 graduate students, postdoctoral fellows, and visiting associates. Many of them are now in leading academic, industrial and governmental positions. Working with such minds in a village of science has been the most rewarding experience – Caltech was the right place for me.

We've just passed a milestone: Twenty years ago, on January 3, 1972, Blue Chip Stamps (then an affiliate of Berkshire and later merged into it) bought control of See's Candy Shops, a West Coast manufacturer and retailer of boxed-chocolates. The nominal price that the sellers were asking - calculated on the 100% ownership we ultimately attained - was $40 million. But the company had $10 million of excess cash, and therefore the true offering price was $30 million. Charlie and I, not yet fully appreciative of the value of an economic franchise, looked at the company's mere $7 million of tangible net worth and said $25 million was as high as we would go (and we meant it). Fortunately, the sellers accepted our offer. The sales of trading stamps by Blue Chip thereafter declined from $102.5 million in 1972 to $1.2 million in 1991. But See's candy sales in the same period increased from $29 million to $196 million. Moreover, profits at See's grew even faster than sales, from $4.2 million pre-tax in 1972 to $42.4 million last year.

In the whole of my career, there were very few training sessions that I missed. Even when I was pregnant, I trained all the way through. I was back training when my daughter was two weeks old. You've got to commit to this, because it can be really easy to walk away from the track, convince yourself, "Oh, well, I'll do it tomorrow, I'll catch up". You can't and what I say is it's all pennies in the bank. When I say that to my daughter, she rolls her eyes at me, but you put a couple of pennies in every day and when it matters, then you've got this bank to call on, as opposed to you can't stick them all in two weeks before.

In Rakuten's case, adjustment certainly took time. At first, meetings often felt awkward. The first board meeting after the Englishization decision took four hours to complete – double the normal duration. But whenever executives asked if they could say certain things in Japanese, I told them no. I knew that the challenge would pay off – and it has.

Getting rich slow isn't actually slower. It's slower in year one, but it might be faster in year seven.

When we started Airbnb, no one wanted to invest. I felt like a failure so many days. It was small, it wasn't growing... A sane person probably would have quit. But we kept going through obscurity, through rejection. We couldn't raise money — but over time, it started growing.