What I'm the most proud of is the opportunity to help City to start the journey to be one of the elite clubs in England now.

Microsoft was at the center of the personal computer revolution, and particularly the creation of a software market where you went out to lots of companies, and encouraged them to write software for different applications, mundane applications, wild applications. That idea that you would encourage people to be creative, and build software, and there would be a whole industry around that.

I think three things. One is the great advances in auto safety. I mean, there are tens of thousands of people being saved every year because cars are safer, and millions of people over a decade, injuries prevented. I think that’s a good example of the need to make technology more humane. We may benefit from a lot of technologies, but they exact a cost. Emphysema, cancer, soil contamination, contaminated water, death and injury on the highway. We’ve got to put more effort on making them more humane.

For a start, the sound of my voice has changed a little bit, which comes [with aging]. But whenever I listen to myself from those ages, I’m proud of myself because I was young, but there’s no music of mine that I listen to and I’m like, “Nah, I wish I didn’t do that.” Everything that I’ve listened to so far, I’m proud of what I did, even at that age.

When I am on my deathbed, and I am thinking back on my life, I am absolutely certain that the thing I will be thinking about is holding my daughters' hands and taking them to the park. It will not be some speech I gave or some legislation that I passed. I am positive about that. And so if you keep that in mind, then you have to invest accordingly.

Security. People naturally resist change in our personal lives. … Malia, actually, was the one who brought it up because she says, 'You know, one of the things that happens is sometimes transitions are hard, and I really enjoy my life, and I like how things are going.' And I said, 'Get in the habit of being able to embrace change, and what's new. Because you don't want to live your life where, you are held back because you've gotten too comfortable, and you are afraid of what might be out there around the corner.'

When I feel as if the people closest to me are happy and healthy and I'm connected with them, and when I feel as if I'm doing things that are making other people better and happy, then I feel real good. That's when I'm at my peak.

If you ask me where has been the one area where I feel that I've been most frustrated and most stymied it is the fact that the United States of America is the one advanced nation on earth in which we do not have sufficient common-sense, gun-safety laws. Even in the face of repeated mass killings. … And for us not to be able to resolve that issue has been something that is distressing. But it is not something that I intend to stop working on in the remaining 18 months.

Nothing comes to my desk that is perfectly solvable. … Otherwise, someone else would have solved it. So you wind up dealing with probabilities. Any given decision you make you'll wind up with a 30 to 40 percent chance that it isn't going to work. You have to own that and feel comfortable with the way you made the decision. You can't be paralyzed by the fact that it might not work out.

People ask me sometimes, who inspires you, Mr. President? Those quiet heroes all across this country -- some of your parents and grandparents who are sitting here -- no fanfare, no articles written about them, they just persevere. They just do their jobs. They meet their responsibilities. They don't quit. I'm only here because of them. They may not have set out to change the world, but in small, important ways, they did. They certainly changed mine.