What is something everyone in your world agrees about that you think is wrong?
Recorded Shinya Yamanaka said elsewhere, not written here
In Japan, however, I found myself suffering from Post America Depression or PAD. The environment for researchers in Japan was quite different in many ways from that in the U.S. At the medical school, very few scientists showed interest in the basic biology of mouse ES cells, and there was little thought-provoking discussion with my colleagues. Some of my colleagues advised me to work on something more related to medicine. Furthermore, I could not get enough funding and had to change the cages of the numerous mice by myself every week. What was worse, the Nat1 work was being rejected by many journals. I felt lonely and depressed, and I was about to give up my career as a scientist and return to the path of physician.

Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 2012 source ↗

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Rahul Dravid India Test and one-day international cricketer, 1996–2012; later India head coach
One of the biggest challenges that the game must respond to today, I believe, is charting out a clear road map for the three formats. We now realise that the sport's three formats cannot be played in equal numbers - that will only throw scheduling and the true development of players completely off gear.
Recorded Bradman Oration, Anzac Hall, Australian War Memorial, Canberra, ESPNcricinfo, 14 December 2011 source ↗
Esther Duflo Development economist; laureate of the Sveriges Riksbank Prize in Economic Sciences, 2019
I think it's … the profession is starting to realise that in part it's the general climate, and the way we treat each other is not conducive for having more women in the profession. It's not just about promotion but it's about the general environment and how people talk to each other and address each other in seminars and things like that, that we need to work on a culture that is more respectful and that will be more acceptable for many women who think that they don't want to play the games of shouting at each other.
Recorded Adam Smith, Telephone interview recorded shortly after the prize announcement, Nobel Prize Outreach, 14 October 2019 source ↗
Maryam Mirzakhani Mathematician; Fields Medallist, 2014
However, I should say that the education system in Iran is not the way people might imagine here. As a graduate student at Harvard, I had to explain quite a few times that I was allowed to attend a university as a woman in Iran. While it is true that boys and girls go to separate schools up to high school, this does not prevent them from participating say in the Olympiads or the summer camps.
Recorded Clay Mathematics Institute annual report interview, Clay Mathematics Institute Annual Report 2008, 1 January 2008 source ↗
Hiroshi Mikitani Founder, chairman and chief executive of Rakuten
Of course, my decision faced plenty of criticism. One of my fellow Japanese CEOs went so far as to call the plan “stupid” – notable, in a country where executives do not generally criticize one another in the press. Clearly, I would have to fight an uphill battle for cultural acceptance. But I was not deterred. A seismic shift demands that we adapt to a new landscape, and a seismic economic shift is exactly what Japan has undergone in recent decades, driven by the forces of globalization and digitization. The only way to compete in this interconnected internet age is to speak the language of the market – and that language is English.
Recorded Mikitani's own essay, originally published on LinkedIn, Inc. (republishing Mikitani's own LinkedIn essay) source ↗

More from Shinya Yamanaka

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Question What are you most proud of? Identity & self
I strongly feel that this is, that I am able to receive this award because of John Gurdon and also many other researchers in the field. This field has a long history, starting with John Gurdon. So I feel very lucky. I may have played some important role in this long history, but it was not myself who initiated this field. So that’s my feeling right now.
Recorded Adam Smith, Telephone interview recorded shortly after the prize announcement, October 2012, Nobel Prize Outreach, 1 October 2012 source ↗
Question What advice would you give your twenty-year-old self, and what should they ignore? Time & hindsight
Well, I will bring this technology to clinics. I really want to help as many patients as possible. As you may know, I started my career as a surgeon 25 years ago. But it turned out that I am not talented as a surgeon
Recorded Adam Smith, Telephone interview recorded shortly after the prize announcement, October 2012, Nobel Prize Outreach, 1 October 2012 source ↗
Question What problem are you still trying to solve? Craft & work
we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology
Recorded Academy of Achievement interviewer, Academy of Achievement interview, 2008 source ↗
Question What inspires you to learn? Attention & the world
I got very interested in so-called “knockout mouse” technology. Knockout mouse is a way to study the function of genes. You know, both human and mouse have approximately 20,000 genes. With knockout mouse technology, we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology. That’s why I decided to move to the States, San Francisco
Recorded Academy of Achievement interviewer, Academy of Achievement interview, 2008 source ↗
Question What is the part of your job that people would be surprised is most of your job? Craft & work
Running CiRA with some 250 staff, I have come to spend less time discussing their data with my colleagues and students, and have been absorbed by my duties as the "chief executive officer" of CiRA, including devising strategies to advance both basic and applied research and to obtain sufficient funding. Anxious about the lack of financial resources for the future to allow us to continue hiring research support staffers, I even ran the full Kyoto Marathon in 2012 to raise online donations from the public. It was hard but helped us raise more than 10 million yen.
Recorded Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 2012 source ↗

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