There are many battles. There’s so much that needs to be done. We need to protect the environment. Save this little planet. Not just this little piece of real estate we call America, but save the planet.

we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology

They have a lot of extreme physics going on inside them and scientists use them to test theories of relativity on a cosmic scale. Einstein’s theories are checking out pretty well so far.

We have all these interesting challenges now. No one knows whether automation and robotics, nanotechnology, will kill more jobs than it creates. If it does, that presents a serious problem. What are we going to do? Have a few of us work to support everybody else, or shorten the workweek for everybody? If so, how do we get from here to there? No one knows yet how we’re going to stop cyber terrorism from wrecking honest discourse in democracy and maybe putting our very lives at risk.

I did have — definitely — one heroic figure who impressed me very much indeed, and that was the great Antarctic explorer, Shackleton. Shackleton I always admired because he was a tough man and a very good leader. And whenever he was in difficult circumstances, which he frequently was, he seemed to have the great ability to inspire his men and lead his party safely out of those conditions. So certainly Shackleton, I would have said, more than anything, was a role model for me.

In the first 33 years of my life which is up until I climbed Everest, I was a very restless and slightly unhappy sort of person. I really didn’t have a great deal of social life, but I’d become very interested in adventurous activities. Perhaps, I was, in some respects something of a loner. But after I got married, that certainly changed my life very considerably, indeed. I found that it was possible to mix having a family with continuing on with adventurous activities, but I think a great deal of that was having a suitable wife. My wife was very, long-suffering. She knew that there were certain things I wanted to do and she was happy that I should do them. She was prepared to put up with considerable periods of being alone with the kids. She, was marvelous, so it made it possible for me to do the things that I wanted to do as well.

I’ve been very fortunate in that respect. In the early days I liked to be the bomb of the expedition, and rush on ahead and do things faster than anybody else. Those days merged very pleasantly into periods when I organized and inspired expeditions and selected these younger people who were then the bombs of the operation. And then it drifted into this involvement with the people of the area, still loving the mountains, but finding the people just as important too. And on and on it’s gone. As I get older and less physically capable, I find other challenges have grown up and become just as important to me.

I personally wouldn’t be, if I could possibly help it, involved in a serious pursuit in which there weren’t a few people who could laugh a bit about it. Because I can remember many occasions — maybe we’ve been stuck in a tent or we’re up on the side of a mountain, this heavy snow, avalanches all around us, and we can’t get up and we can’t get down, but we just sat in the tent and reminisced about occasions and days gone by and laughed about old jokes and all the rest of it. Then you really have a very good time, even though you’re sort of poised there between disaster both up and down. People who can make you laugh under those circumstances are very valuable indeed in an expedition.

I think motivation is the single most important factor in any sort of success. Physical fitness is important, technical skill is important, and maybe even the desire for money is important in some respects. But a sort of basic motivation, the desire to succeed, to stretch yourself to the utmost is the most important factor. Certainly in the field of exploration and activity, it’s the thing that makes the difference between someone who does really well and someone who doesn’t.

My mother used to say to me a thing which, when I look back on it, wasn’t terribly logical. — and I had a pretty hearty appetite, but when I had had a large meal put in front of me, and even I couldn’t get through it, she would say, “Edmund, remember the starving millions in Asia.” Now what possible use my consuming it would do for the starving millions in Asia, I don’t really know, but the fact remains that I was brought up to think about the starving millions in Asia. That meant I had to clean my plate up and not waste it. Later on, I got more involved with the starving millions in Asia, perhaps in a slightly more practical way: helping some of them with schooling and hospitaling and even in agriculture.