When I have a sense that things are screwed up, and I’m just not sure whether or not we’ll find an answer, the thing I do is usually sit at the piano, and I play a song by Beethoven called Para Elisa (Für Elise)

You cannot tell from appearances how things will go. Sometimes imagination makes things out far worse than they are; yet without imagination not much can be done. Those people who are imaginative see many more dangers than perhaps exist; certainly many more than will happen; but then they must also pray to be given that extra courage to carry this far-reaching imagination.

Now I try to protect one hour in the morning and one in the afternoon where I turn off Slack, and I don't check email. I might read, or write in a journal, or just go for a walk. It's become one of the most important parts of my day. It's when I'm most creative, and when I hit on ideas that can take the company in new directions.

While I’m on stage, you are all my guests, because that’s sort of the unsaid agreement. While you’re my guest, if something bad happens on stage, I often think of Julia Child, “Oh, the chicken’s fallen on the floor! Yes. Oh, well pick it up and put it right back.” And you know what? Everybody’s with you. […] So whatever you practice for on the engineering side that fails is all right, because we have a greater purpose. The greater purpose is that we’re communing together and we want this moment to be really special for all of us. Because otherwise, why bother to have come at all? It’s not about proving anything. It’s about sharing something.

First of all, I believe that the results of science should be fully given to the community. Fully. Absolutely. And all types of competition such as who did it first and “I cannot tell him because he will copy me” and so on – these are not arguments. Society financed this science, if not directly, then the education and the way I got there, so society should get back what I found. It is not my finding. In this, I am not very popular, I must say.

Today, in my opinion, people are more interested in the number of papers and the way of judging people has become much more statistical. Pupils are already doing this right from the beginning. Also, very few people go into basic science, there’s a big thing about making money e.g. biotech. Some people view education as a tool for making money or at least for making a good life, rather than understanding and digging down into something, which was my motivation.

I look for how to get out of it. I try to use here [points to her head]. I tried to read, I tried to talk to others. I tried my best to get out of it. I had lots of times climbing one Everest to find that there is a bigger Everest, but don’t you find your life like this too?

I still don’t understand everything about the ribosome. I must say that the more lectures I give and the more questions that I get, the more thoughts they trigger. And also, we are now interested in the proto-ribosome, how life started. So we are trying to understand this and this really excites me, not just from the point of view of philosophy, we are trying to show it.

Try to make better antibiotics. I’m not sure we can cure everything, that we can win the game against bacteria, but we can try to control it, to make the appearance of resistance more controllable. We can look for new antibiotics, not overuse antibiotics, not use antibiotics where they are not needed. If possible, if somebody has an idea for something completely new, I would love that.

Ultimately, my research was curiosity driven, which kept me active even in low periods.