There is always an impulse to degrade people who are different from you, to diminish them, to demean them, and it never seems to go away, even when there is ample evidence that when we work together, we do better. It’s not about material progress or personal comfort. It’s about personal identity, and there are still so many forces at work in the human psyche that lead some people to think that their identity requires them to have someone to look down on or to demean or to feel that they’re superior to, and I think that that’s at the root of all this. It’s the only story in human society. Who is the other? Who is one of yours? Cain and Abel.

I was forced to think very hard about what it meant to be me, what it means to be a person who is only a brain. Pascal's 'thinking reed' really does capture it, because I'm just a bunch of dead muscles thinking.

The stroke cut out a lot of my external trips: my sports car and golf and my cello. This [ points to hand ] is just not much use with a cello, and I was—forced inside, and finding myself living in my inside. And that has made me be part of my soul. And that's perceiving my incarnation from here [ points to heart ], rather than from here [ points to head ]. And since this is words, I start from here, go over there.

The problem is I'm older now, I'm 40 years old, and this stuff doesn't change the world. It really doesn't. That's going to break people's hearts. I'm sorry, it's true. Having children really changes your view on these things. We're born, we live for a brief instant, and we die.

I believe that if, at the end, according to our abilities, we have done something to make others a little happier, and something to make ourselves a little happier, that is about the best we can do. To make others less happy is a crime. To make ourselves unhappy is where all crime starts. We must try to contribute joy to the world. That is true no matter what our problems, our health, our circumstances. We must try. I didn’t always know this and am happy I lived long enough to find it out.

Many readers have informed me that it is a tragic and dreary business to go into death without faith. I don’t feel that way. “Faith” is neutral. All depends on what is believed in. I have no desire to live forever. The concept frightens me. I am 69, have had cancer, will die sooner than most of those reading this. That is in the nature of things.

What I expect to happen is that my body will fail, my mind will cease to function and that will be that. My genes will not live on, because I have had no children. I am comforted by Richard Dawkins’ theory of memes. Those are mental units: thoughts, ideas, gestures, notions, songs, beliefs, rhymes, ideals, teachings, sayings, phrases, clichés that move from mind to mind as genes move from body to body. After a lifetime of writing, teaching, broadcasting and telling too many jokes, I will leave behind more memes than many. They will all also eventually die, but so it goes.

What I expect to happen is that my body will fail, my mind will cease to function and that will be that. My genes will not live on, because I have had no children. I am comforted by Richard Dawkins’ theory of memes. Those are mental units: thoughts, ideas, gestures, notions, songs, beliefs, rhymes, ideals, teachings, sayings, phrases, clichés that move from mind to mind as genes move from body to body. After a lifetime of writing, teaching, broadcasting and telling too many jokes, I will leave behind more memes than many. They will all also eventually die, but so it goes.

Thank God I found sobriety. I could sustain myself with my work, my reading, the movies, my friends. And walking, walking, walking. Of all the purposes of education, I think the most useful is this: It prepares you to keep yourself entertained. It gives you a better chance of an interesting job. ... I can't remember the last time I felt bored. I can't eat, drink or talk, and yet I have so many other resources to keep myself entertained. I think I must be a case study.

One of these days I will encounter what Henry James called on his deathbed “the distinguished thing.” I will not be conscious of the moment of passing. In this life I have already been declared dead. It wasn’t so bad. After the first ruptured artery, the doctors thought I was finished. My wife, Chaz, said she sensed that I was still alive and was communicating to her that I wasn’t finished yet. She said our hearts were beating in unison, although my heartbeat couldn’t be discovered. She told the doctors I was alive, they did what doctors do, and here I am, alive.