Tu Youyou

In Ge Hong's A Handbook of Prescriptions for Emergencies (肘后备急方), I noticed one sentence "A handful of Qinghao immersed in two liters of water, wring out the juice and drink it all" (青蒿一握, 以水二升渍, 绞取汁, 尽服之) when Qinghao was mentioned for alleviating malaria fevers. Most herbs were typically boiled in water and made into a decoction before taken by the patients. This unique way of using Qinghao gave me the idea that heating during extraction might have destroyed the active components and the high temperature might need to be avoided in order to preserve the herb's activity.

Recorded · Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 2015 · source

Most pharmaceutical workshops were shut down during the great cultural revolution. Without manufacturing support, we had to extract herbs ourselves using household vats etc. The team worked very long hours every day including the weekends. Due to lack of proper equipment and ventilation, and long-term exposure to the organic solvents, some of my team members included myself started to show unhealthy symptoms. This, however, did not stop our efforts.

Recorded · Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 2015 · source

I unfortunately contracted tuberculosis at the age of sixteen and had to take a two-year break and receive treatment at home before I resumed my study at the private Ningbo Xiaoshi High School (1948–1950) and Ningbo High School (1950–1951). This experience led me to make a decision to choose medical research for my advanced education and career – if I could learn and have (medical) skills, I could not only keep myself healthy but also cure many other patients.

Recorded · Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 2015 · source