Let us consider me as a test case. As I have said, I would like to die peacefully with Thomas Tallis on my iPod before the disease takes me over and I hope that will not be for quite some time to come, because if I knew that I could die at any time I wanted, then suddenly every day would be as precious as a million pounds. If I knew that I could die, I would live. My life, my death, my choice.

And so it’s true; I think what I said on that post is that every day since my mom died, there hasn’t been a day that I haven’t thought about my own death. That’s true. And I don’t think about it in a morbid way, but I think of it in a way that I’m aware of not taking my life for granted and not taking your life for granted, or any of our lives for granted.

what’s the difference? If I die in two years’ time, what will I do between now and then which I don’t want to do now? The main reason for living longer now is for the sake of my family and my wife. And this is not rationalist bravado entirely. I’ve had a wonderful life. Yes, I’ve done a lot of things I shouldn’t have done. But you know, I’ve had a full, complete life, and there’s nothing more I can do to complete it. Dying when you’re younger is obviously a totally different situation. Or losing a child. I mean, that’s beyond words.

Every 90 days I lie in a whirling CT machine, dye coursing through my veins, and the doctors look to see whether the tumors in my liver are growing. If they are not, the doctors smile and schedule another scan. The rhythm has been the same since my doctors told me I had stage IV colon cancer two and a half years ago. I live for three months, take a deep breath and hope to start over again. I will probably do this for the rest of my life. Whatever that means.

The peace of the Sabbath, of a stopped world, a time outside time, was palpable, infused everything, and I found myself drenched with a wistfulness, something akin to nostalgia, wondering what if: What if A and B and C had been different? What sort of person might I have been? What sort of a life might I have lived?

I cannot pretend I am without fear. But my predominant feeling is one of gratitude. I have loved and been loved; I have been given much and I have given something in return; I have read and traveled and thought and written. I have had an intercourse with the world, the special intercourse of writers and readers. Above all, I have been a sentient being, a thinking animal, on this beautiful planet, and that in itself has been an enormous privilege and adventure.

And I spent four years at a boarding school in the country, probably a rather abusive boarding school, and seeing very little of my parents, and that was a very bad time for me. A bad and almost a mad time. ... I think that some sort of trust, and ability for closeness, may have been compromised. And I think I’ve perhaps, to some extent, sort of kept a distance since that time, although this is not a distance I feel with my patients or my students.

My generation is on the way out, and each death I have felt as an abruption, a tearing away of part of myself. There will be no one like us when we are gone, but then there is no one like anyone else, ever. When people die, they cannot be replaced. They leave holes that cannot be filled, for it is the fate — the genetic and neural fate — of every human being to be a unique individual, to find his own path, to live his own life, to die his own death.

The first biography I read — I think the first scientific biography — was Madame Curie . And my mother, who was a surgeon, worked at the Marie Curie Hospital. She’d met Marie Curie, who was one of her great heroines. And reading the book, I think, was the first portrait of a scientist and the romance of a scientific life.

I’ve had this concern all the time, but I can only hope that if one writes with appreciation and delicacy and respect, then it’s okay. I have to say that I’ve written a hundred times as much as I’ve published, because if there’s any thought of offense or embarrassment, then I will put the thing quietly away.