For the last few weeks, I've been completely happy. I've got my next PSA in three weeks' time. It may well show my PSA is starting to go up, and the cancer's coming back. Totally to my surprise, I've acquired this sort of Buddhist Zen outlook. Well, the future doesn't exist. I'm well. I'm happy at the moment. I've had a wonderful, exciting life. I've made lots of mistakes. I've trampled on people - yak, yak, yak, as I discuss in my books. But at the moment, today, the sun is shining. I'm very well. It's not that I'm in denial, but I think, well, all right. It may be bad news in three weeks' time, but that's three weeks away. At the moment, I'm well.

Many of us had moments when we doubted that apartheid would be defeated, certainly not in our lifetime. But, I never had that sense. I knew in a way that was unshakable, because you see, when you look at something like Good Friday, and saw God dead on the cross, nothing could have been more hopeless than Good Friday. And then, Easter happens, and whammo! Death is done to death, and Jesus breaks the shackles of death and devastation, of darkness, of evil. And, from that moment on, you see, all of us are constrained to be prisoners of hope. If God could do this with that utterly devastating thing, the desolation of a Good Friday, of the cross, well, what could stop God then from bringing good out of this great evil of apartheid? So, I never doubted that ultimately we were going to be free because ultimately, I knew there was no way in which a lie could prevail over the truth, darkness over light, death over life.

During the day I can at least request a scratch, an adjustment, a drink, or simply a gratuitous re-placement of my limbs—since enforced stillness for hours on end is not only physically uncomfortable but psychologically close to intolerable. It is not as though you lose the desire to stretch, to bend, to stand or lie or run or even exercise. But when the urge comes over you there is nothing—nothing—that you can do except seek some tiny substitute or else find a way to suppress the thought and the accompanying muscle memory.

Yeah, there were a lot of brave people who stood up. Then, you know, it cost Martin Luther King and Medgar Evers and the three civil rights workers in Philadelphia, Mississippi, and Viola Liuzza and a lot of the others their lives, but they were on the right side of history, and they believed if they made this sacrifice that it would work out. And whenever I get discouraged about everything they stood against rising up again, I realize there just are no public, or permanent, victories. You have to keep fighting for freedom.

I continued the work on dorsal, discovered the recessive phenotype and interpreted the phenotype postulating a gradient determining the dorsoventral axis. At that time, gradients were not widely accepted as mechanisms, in particular biochemists were highly sceptical, however the Tübingen influence made such models attractive to me.

I don’t think it’s misused yet, people are afraid of it might be misused but on the other hand, there is also value in finding out about the relation between several particular predispositions. You might be more careful if you are told that your genetic background is such that you shouldn’t eat fat in large amounts or so, it does help you change your life a little bit and so it’s not so bad, but it’s hard to find out which genetic background is causing these things.

so I sometimes think, why should I talk young women into being a scientist if they then end up being sort of disliked or not accepted by their contemporaries and so it’s a tricky business actually.

I immediately loved working with flies. They fascinated me, and followed me around in my dreams.

Not really. I thought that getting the Nobel Prize was a big interruption in my career, I thought and it was very distracting. It takes a lot of time you know, it just takes time to be honoured, you have to travel and you have to give speeches of things you have, oh it’s so often that you get bored to tears when you hear your own voice. And it’s really taking a lot of your time and there’s no way that during this time you can start something new, I mean you just profit from what you’ve done and there is no time to develop new ideas.

I felt at the time that Eric was much more successful than I, he was extremely productive during his time in Zurich, and worked on many very original projects, germ line, cell lineage, sex determination, where not many people could follow him. I also had the impression that I was dependent on him because he had more fly experience and without him I would not have gotten the job. This made our start in Heidelberg a little difficult, until we sorted things out, and from then on we thoroughly enjoyed working in the same lab.