I would end every night reading these ten letters. It made the numbers and the policies very concrete and very specific. And I was reminded that the choices we were making were affecting millions of people. I found that to be very useful.

one of my diseases, one of my things in life, is that anything that is secret I try to undo. And so the locks to those filing cabinets represented a challenge to me. How the hell to open them? So I worked and worked on them. There are all kinds of stories about how you can feel the numbers and listen to things and so on. That's true; I understand it very well - for old- 19 fashioned safes. But these had a new design so that nothing would be pushing against the wheels while you were trying them, and none of the old methods would work. I read books by locksmiths, which always say in the beginning how they opened the locks when the safe is under water and the woman in it is drowning or some-thing, and the great locksmith opened the safe. And then in the back they tell you how they do it, and they don't tell you anything sensible. It doesn't sound like they could really open safes that way — like guess the combination on the basis of the psychology of the person who owns it! So I always figured they were keeping the method a secret, and like a kind of disease, I kept working on these things until I found out a few things. First, I found out how big a range you need to open the combination, how close you have to be. And then I invented a system by which you could try all the necessary combinations - 8,000, as it turned out, because the woman DROWNING عزه Books are always telling how the great locksmith opens the safe under water when the woman in it is drowning. 20 you could be within two of every number. And then I worked out a scheme by which I could try numbers without altering a number that I had already set, by correctly moving the wheels, so that I could try all the combinations in eight hours. And then finally I discovered (this took me about two years of researching) that it's easy to take the last two numbers of the combination off the safe if the safe is open. If the drawer was pulled out, you could turn the number and see the bolt go up and play around and find out what number it comes back at, and stuff like that. With a little trickery, you can get the combination off. So I used to practice it like a cardsharp practices cards, you know - all the time. Quicker and quicker and more and more unobtrusively I would come in and talk to some guy. I'd sort of lean against his filing cabinet, and you wouldn't even notice I'm doing any-thing. I'm not doing anything— just playing with the dial, that's all, just playing with the dial. But all the time I was taking the two numbers off! And then I would go back to my office and write the two numbers down, the last two numbers of the three. Now, if you have the last two numbers, it takes just a minute to try for the first number; there's only 20 possibilities, and it's open. OK? It takes about three minutes to open a safe if you know the last two numbers. So I got an excellent reputation for safe-cracking.

What we've done all of these years is very simple, is use the little tool, which is ask three whys in a row. Because the first why you always have a good answer for. The second why, it starts getting difficult. By the third why, you don't really know why you're doing what you're doing.

Well actually I was at home. I was doing some housework. So I was very surprised.

I think a very big curiosity. I’m very curious and I like to understand things and not only science but also other things where I just try to find out why things work or how things work. Science and nature caught my attention as a small child already. I was growing up in a city but we had a garden and I loved the garden and then often on vacation I was at a farm and I loved these animals and plants and so on, so I was attracted very early on and then we had a very good teaching actually at my … I don’t know whether my teachers really had much of a role because I was determined very early, but then I also did music and I did languages and Literature and so on. I have broad interests actually other than science, but this is really true, this curiosity.

As I was lazy and rarely did my homework, I finished high school with a rather mediocre exam. I almost did not pass in English language. Recently, my previous teachers allowed me to see their report on my high school performances, which included the following statements: Despite the fact that her talents are rather equally spread among many areas of knowledge, her performances are rather different depending on the distribution of her interests. Thus, with her strong display of self will she can be decidedly lazy in some topics over years, while in her areas of interests she performs to a degree far extending that required for normal school purposes.

Not really. I thought that getting the Nobel Prize was a big interruption in my career, I thought and it was very distracting. It takes a lot of time you know, it just takes time to be honoured, you have to travel and you have to give speeches of things you have, oh it’s so often that you get bored to tears when you hear your own voice. And it’s really taking a lot of your time and there’s no way that during this time you can start something new, I mean you just profit from what you’ve done and there is no time to develop new ideas.

so I sometimes think, why should I talk young women into being a scientist if they then end up being sort of disliked or not accepted by their contemporaries and so it’s a tricky business actually.

They were blocked in their minds to do this because they thought, oh this is not done, we don’t do that in our field and you can’t do that, and I said: Why not?

I don’t think it’s misused yet, people are afraid of it might be misused but on the other hand, there is also value in finding out about the relation between several particular predispositions. You might be more careful if you are told that your genetic background is such that you shouldn’t eat fat in large amounts or so, it does help you change your life a little bit and so it’s not so bad, but it’s hard to find out which genetic background is causing these things.