The question

Which problem are you still chipping away at?

Originally asked

Lifehacker, to people about their working day, How I Work

Lifehacker repeatedly used this exact closing prompt in its named How I Work questionnaire.

You answer as yourself. Nobody on FLAPSS answers as anybody else.

Christiane Nüsslein-Volhard

Developmental biologist; Nobel laureate in Physiology or Medicine, 1995

Recorded said elsewhere, not written here
we know the fish, we know the worm, we know the fly, but we don’t know the links between and we don’t know, when we go back to the branches in evolution, we really don’t know what happened there when they branched and how they divert and what is the major drive for evolution.

Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗

Others on this question

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John Lewis U.S. Representative from Georgia, 1987–2020; Chairman of the Student Nonviolent Coordinating Committee 1963–1966
There are many battles. There’s so much that needs to be done. We need to protect the environment. Save this little planet. Not just this little piece of real estate we call America, but save the planet.
Recorded Academy of Achievement interview, Chicago, 10 June 2004 source ↗
Shinya Yamanaka Stem cell biologist; Nobel laureate in Physiology or Medicine, 2012
we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology
Recorded Academy of Achievement interviewer, Academy of Achievement interview, 2008 source ↗
Desmond Tutu Anglican Archbishop of Cape Town; chair of South Africa’s Truth and Reconciliation Commission; Nobel Peace Prize, 1984
So a great deal has changed, but we in the Truth and Reconciliation Commission said, “Watch it. You can kiss reconciliation and forgiveness goodbye, unless the gap between the rich and the poor — the haves and the have-nots — is narrowed, and narrowed quickly and dramatically.” So yes, we face very, very considerable problems.
Recorded Academy of Achievement interview source ↗
Mario Molina Atmospheric chemist; Nobel laureate in Chemistry, 1995
I certainly want to continue trying to understand how the global environment functions. The earth as a system is a very complicated one. And to understand it, we need very many disciplines, very many different scientists working together. I want to continue working with my specialty, which is chemistry, with the atmosphere. There is still much to learn about chemical reactions that occur out there in the air, in the atmosphere. So one of my projects now is to really learn more about this pollution that occurs in cities and that is spreading more through the globe. To learn it in enough detail so we can better tackle it, we can better come up with new ways of using energy, for example, that are not so damaging to the environment.
Recorded Academy of Achievement interview, Sun Valley, Idaho, 29 June 1996 source ↗

More from Christiane Nüsslein-Volhard

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Question Which teacher, parent, coach, or friend most made you who you are, and what did you learn from them? Relationships
we had a wonderful education because my parents were so practical … Christiane Nüsslein-Volhard: Yes I mean, I have a strong likeness of culture and also I mean my grandmother was a painter and we do music in the family quite a lot and I think that’s very important. What was also important, I thought about that recently, also maybe as a follow-up of an interview but I was asked what my parents did and so on and looking at my brothers and sisters, we had a wonderful education because my parents were so practical, they did books themselves and we did a lot of handicrafts and I knew how to knit and sew and cook and we learnt a lot to do things ourselves, to make things ourselves so we all have some dexterity in doing things ourselves and this is also very important for Science
Recorded Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗
Question What do you need to believe in order to get through an ordinary day? Values & belief
I sing yes sure and I garden, I have a large garden and I really recreate myself by doing gardening and thinking about something else so that when your mind gets free from all the burden of the daily troubles and then you can start putting something fresh in, you know.
Recorded Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗
Question What does everyone in your world seem to agree on that you think is wrong? Values & belief
I continued the work on dorsal, discovered the recessive phenotype and interpreted the phenotype postulating a gradient determining the dorsoventral axis. At that time, gradients were not widely accepted as mechanisms, in particular biochemists were highly sceptical, however the Tübingen influence made such models attractive to me.
Recorded Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 1995 source ↗
Question What lesson has mattered most in your life? Time & hindsight
Not really. I thought that getting the Nobel Prize was a big interruption in my career, I thought and it was very distracting. It takes a lot of time you know, it just takes time to be honoured, you have to travel and you have to give speeches of things you have, oh it’s so often that you get bored to tears when you hear your own voice. And it’s really taking a lot of your time and there’s no way that during this time you can start something new, I mean you just profit from what you’ve done and there is no time to develop new ideas.
Recorded Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗
Question What makes you want to keep learning? Attention & the world
I think a very big curiosity. I’m very curious and I like to understand things and not only science but also other things where I just try to find out why things work or how things work. Science and nature caught my attention as a small child already. I was growing up in a city but we had a garden and I loved the garden and then often on vacation I was at a farm and I loved these animals and plants and so on, so I was attracted very early on and then we had a very good teaching actually at my … I don’t know whether my teachers really had much of a role because I was determined very early, but then I also did music and I did languages and Literature and so on. I have broad interests actually other than science, but this is really true, this curiosity.
Recorded Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗

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