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Christiane Nüsslein-Volhard

Developmental biologist; Nobel laureate in Physiology or Medicine, 1995

Germany · b. 1942

Developmental biologist and director emerita at the Max Planck Institute for Biology in Tübingen. Shared the 1995 Nobel Prize in Physiology or Medicine with Eric Wieschaus and Edward Lewis for identifying genes that control segmentation in the Drosophila embryo. The screens she and Wieschaus ran at the European Molecular Biology Laboratory in 1979 and 1980 became a standard method in the field.

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I continued the work on dorsal, discovered the recessive phenotype and interpreted the phenotype postulating a gradient determining the dorsoventral axis. At that time, gradients were not widely accepted as mechanisms, in particular biochemists were highly sceptical, however the Tübingen influence made such models attractive to me.

Recorded Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 1995 source

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