When you’re a carpenter making a beautiful chest of drawers, you’re not going to use a piece of plywood on the back, even though it faces the wall and nobody will ever see it. You’ll know it’s there, so you’re going to use a beautiful piece of wood on the back. For you to sleep well at night, the aesthetic, the quality, has to be carried all the way through.

Charlie and I decided long ago that in an investment lifetime it's just too hard to make hundreds of smart decisions. That judgment became ever more compelling as Berkshire's capital mushroomed and the universe of investments that could significantly affect our results shrank dramatically. Therefore, we adopted a strategy that required our being smart - and not too smart at that - only a very few times. Indeed, we'll now settle for one good idea a year. (Charlie says it's my turn.)

I don't enjoy it but I know that I have got to live with [myself] if I'm not going to give it 100 per cent. The key thing is getting to the start line and knowing that I couldn't have done any more, that I didn't back off. You accept the pain, because if you didn't there would always be that element of doubt.

Proceed slowly and take care. […] To ensure that you proceed slowly, write by hand.

we know the fish, we know the worm, we know the fly, but we don’t know the links between and we don’t know, when we go back to the branches in evolution, we really don’t know what happened there when they branched and how they divert and what is the major drive for evolution.

so I sometimes think, why should I talk young women into being a scientist if they then end up being sort of disliked or not accepted by their contemporaries and so it’s a tricky business actually.

I sing yes sure and I garden, I have a large garden and I really recreate myself by doing gardening and thinking about something else so that when your mind gets free from all the burden of the daily troubles and then you can start putting something fresh in, you know.

As I was lazy and rarely did my homework, I finished high school with a rather mediocre exam. I almost did not pass in English language. Recently, my previous teachers allowed me to see their report on my high school performances, which included the following statements: Despite the fact that her talents are rather equally spread among many areas of knowledge, her performances are rather different depending on the distribution of her interests. Thus, with her strong display of self will she can be decidedly lazy in some topics over years, while in her areas of interests she performs to a degree far extending that required for normal school purposes.

we had a wonderful education because my parents were so practical … Christiane Nüsslein-Volhard: Yes I mean, I have a strong likeness of culture and also I mean my grandmother was a painter and we do music in the family quite a lot and I think that’s very important. What was also important, I thought about that recently, also maybe as a follow-up of an interview but I was asked what my parents did and so on and looking at my brothers and sisters, we had a wonderful education because my parents were so practical, they did books themselves and we did a lot of handicrafts and I knew how to knit and sew and cook and we learnt a lot to do things ourselves, to make things ourselves so we all have some dexterity in doing things ourselves and this is also very important for Science

I think a very big curiosity. I’m very curious and I like to understand things and not only science but also other things where I just try to find out why things work or how things work. Science and nature caught my attention as a small child already. I was growing up in a city but we had a garden and I loved the garden and then often on vacation I was at a farm and I loved these animals and plants and so on, so I was attracted very early on and then we had a very good teaching actually at my … I don’t know whether my teachers really had much of a role because I was determined very early, but then I also did music and I did languages and Literature and so on. I have broad interests actually other than science, but this is really true, this curiosity.